Rab8a restores diverse innate functions in CD11c+CD11b+ dendritic cells from aged mice
Abstract Age-related alterations of the immune system compromise the host’s ability to respond to pathogens, but how immune aging is regulated is still poorly understood. Here, we identify via transcriptomic analysis of splenic DCs and bone marrow derived dendritic cells (BMDC) of young and aged mic...
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| Main Authors: | Sudhakar Singh, Azeez Tehseen, Surbhi Dahiya, Yuviana J. Singh, Roman Sarkar, Sharvan Sehrawat |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-54757-2 |
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