Rab8a restores diverse innate functions in CD11c+CD11b+ dendritic cells from aged mice

Abstract Age-related alterations of the immune system compromise the host’s ability to respond to pathogens, but how immune aging is regulated is still poorly understood. Here, we identify via transcriptomic analysis of splenic DCs and bone marrow derived dendritic cells (BMDC) of young and aged mic...

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Bibliographic Details
Main Authors: Sudhakar Singh, Azeez Tehseen, Surbhi Dahiya, Yuviana J. Singh, Roman Sarkar, Sharvan Sehrawat
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54757-2
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