Preeclampsia, Hypoxia, Thrombosis, and Inflammation
Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine grow...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2012/374047 |
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| _version_ | 1832552341395472384 |
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| author | Amir A. Shamshirsaz Michael Paidas Graciela Krikun |
| author_facet | Amir A. Shamshirsaz Michael Paidas Graciela Krikun |
| author_sort | Amir A. Shamshirsaz |
| collection | DOAJ |
| description | Reductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine growth restriction (IUGR). |
| format | Article |
| id | doaj-art-1422f956480546278bf72ae0270adb83 |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-1422f956480546278bf72ae0270adb832025-02-03T05:58:53ZengWileyJournal of Pregnancy2090-27272090-27352012-01-01201210.1155/2012/374047374047Preeclampsia, Hypoxia, Thrombosis, and InflammationAmir A. Shamshirsaz0Michael Paidas1Graciela Krikun2Department of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Yale University, New Haven, CT 06520, USADepartment of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Yale University, New Haven, CT 06520, USADepartment of Obstetrics, Gynecology and Reproductive Sciences, School of Medicine, Yale University, New Haven, CT 06520, USAReductions in uteroplacental flow initiate a cascade of molecular effects leading to hypoxia, thrombosis, inflammation, and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their relationship to preeclampsia (PE) and intrauterine growth restriction (IUGR).http://dx.doi.org/10.1155/2012/374047 |
| spellingShingle | Amir A. Shamshirsaz Michael Paidas Graciela Krikun Preeclampsia, Hypoxia, Thrombosis, and Inflammation Journal of Pregnancy |
| title | Preeclampsia, Hypoxia, Thrombosis, and Inflammation |
| title_full | Preeclampsia, Hypoxia, Thrombosis, and Inflammation |
| title_fullStr | Preeclampsia, Hypoxia, Thrombosis, and Inflammation |
| title_full_unstemmed | Preeclampsia, Hypoxia, Thrombosis, and Inflammation |
| title_short | Preeclampsia, Hypoxia, Thrombosis, and Inflammation |
| title_sort | preeclampsia hypoxia thrombosis and inflammation |
| url | http://dx.doi.org/10.1155/2012/374047 |
| work_keys_str_mv | AT amirashamshirsaz preeclampsiahypoxiathrombosisandinflammation AT michaelpaidas preeclampsiahypoxiathrombosisandinflammation AT gracielakrikun preeclampsiahypoxiathrombosisandinflammation |