Transcriptional profiling reveals H.pylori-associated genes induced inflammatory cell infiltration and chemoresistance in gastric cancer

Transcriptional profiling reveals H.pylori-associated genes induced inflammatory cell infiltration and chemoresistance in gastric cancer

BackgroundH. pylori infection is closely associated with the tumor microenvironment (TME) in gastric cancer (GC), yet its underlying mechanism is elusive. Hence, it is imperative to explore the microenvironment and drug resistance arising from H. pylori to enhance therapeutic strategies for GC.Metho...

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Main Authors: Jinshui Tan, Zhengxin Wu, Yuankun Liu, Wei Wang, Wenjuan Qin, Guangchao Pan, Yubo Xiong, Jingsong Ma, Jiabao Zhao, Huiwen Zhou, ZhengJin Liu, Haijie Lu, Huiqin Zhuo, Xuehui Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
gastric cancer
H. pylori
tumor microenvironment
HspB2
ACSM5
eosinophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592558/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1592558/full

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