Impact of Overnight Storage of Human Atrial Myocytes on Intracellular Calcium Homeostasis and Electrophysiological Utility

Impact of Overnight Storage of Human Atrial Myocytes on Intracellular Calcium Homeostasis and Electrophysiological Utility

Human atrial myocytes afford an attractive experimental model to investigate mechanisms underlying electrophysiological alterations in cardiovascular disease. However, this model presents limitations, such as the availability of human atrial tissue and a variable yield of myocytes isolation. Therefo...

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Bibliographic Details
Main Authors: Cristina Aceituno, David Revuelta, Verónica Jiménez-Sábado, Antonino Ginel, Cristina E. Molina, Leif Hove-Madsen
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
human atrial myocyte
patch-clamp technique
calcium homeostasis
sarcoplasmic reticulum
calcium currents
beat-to-beat response
Online Access:https://www.mdpi.com/2218-273X/14/11/1415
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