β-Resorcylic acid prevents MASLD in ob/ob mice by modulating lipid metabolism and inflammation in the liver

β-Resorcylic acid prevents MASLD in ob/ob mice by modulating lipid metabolism and inflammation in the liver

Metabolic dysfunction-associated steatotic liver disease (MASLD) represents a significant global health challenge. MALSD is primarily driven by metabolic dysfunction, including mitochondrial dysregulation. Here, we show that β-resorcylic acid (β-RA), a naturally derived phenolic molecule known to ta...

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Bibliographic Details
Main Authors: Sergio López-Herrador, Sara Torres-Rusillo, Pilar González-García, Laura Jiménez-Sánchez, Julia Corral-Sarasa, Mohammed Bakkali, M. Elena Díaz-Casado, Luis C. López
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Pharmacological Research
Subjects:
β-resorcylic acid
MASLD
MASH
Leptin-deficient model
Hepatic steatosis
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825003317
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