Distinct steps of neural induction revealed by Asterix, Obelix and TrkC, genes induced by different signals from the organizer.

The amniote organizer (Hensen's node) can induce a complete nervous system when grafted into a peripheral region of a host embryo. Although BMP inhibition has been implicated in neural induction, non-neural cells cannot respond to BMP antagonists unless previously exposed to a node graft for at...

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Bibliographic Details
Main Authors: Sonia Pinho, Pamela R Simonsson, Katherine E Trevers, Matthew J Stower, William T Sherlock, Mohsin Khan, Andrea Streit, Guojun Sheng, Claudio D Stern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0019157
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