A DNA alteration and methylation co-detection method for clinical purpose

A DNA alteration and methylation co-detection method for clinical purpose

Abstract Traditional approaches for capturing genomic alterations and DNA methylation require separate assays, complicating clinical workflows and limiting sample utilization, particularly with low-input materials like cell-free DNA. To address these challenges, we introduce a streamlined approach c...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiyan Yu, Chunhe Yang, Xintao Zhu, Zhankun Wang, Boping Xu, Ye Cai, Jingbo Zhao, Ruijian Guo, Wuzhou Yuan, Jianqing Wang, Bohao Dong, Frank Ron Zheng, Shuang Yang
Format: Article
Language:English
Published: Springer Nature 2025-06-01
Series:EMBO Molecular Medicine
Subjects:
Mutation
Methylation
Co-detection
Minimal Residual Disease
Companion Diagnostics
Online Access:https://doi.org/10.1038/s44321-025-00259-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s44321-025-00259-7

Similar Items