qBiCo: a method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements
Abstract Background Human DNA methylation profiling offers great promises in various biomedical applications, including ageing, cancer and even forensics. So far, most DNA methylation techniques are based on a chemical process called sodium bisulfite conversion, which specifically converts non-methy...
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Main Authors: | Faidra Karkala, Roy B. Simons, Floor Claessens, Vivian Kalamara, Manfred Kayser, Athina Vidaki |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Epigenetics Communications |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43682-025-00033-3 |
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