A Deep Learning–Enabled Workflow to Estimate Real-World Progression-Free Survival in Patients With Metastatic Breast Cancer: Study Using Deidentified Electronic Health Records

A Deep Learning–Enabled Workflow to Estimate Real-World Progression-Free Survival in Patients With Metastatic Breast Cancer: Study Using Deidentified Electronic Health Records

Abstract BackgroundProgression-free survival (PFS) is a crucial endpoint in cancer drug research. Clinician-confirmed cancer progression, namely real-world PFS (rwPFS) in unstructured text (ie, clinical notes), serves as a reasonable surrogate for real-world indicators in asce...

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Main Authors: Gowtham Varma, Rohit Kumar Yenukoti, Praveen Kumar M, Bandlamudi Sai Ashrit, K Purushotham, C Subash, Sunil Kumar Ravi, Verghese Kurien, Avinash Aman, Mithun Manoharan, Shashank Jaiswal, Akash Anand, Rakesh Barve, Viswanathan Thiagarajan, Patrick Lenehan, Scott A Soefje, Venky Soundararajan
Format: Article
Language:English
Published: JMIR Publications 2025-05-01
Series:JMIR Cancer
Online Access:https://cancer.jmir.org/2025/1/e64697
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https://cancer.jmir.org/2025/1/e64697

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