What is the best cutoff point of leukocyte esterase for diagnosis of periprosthetic joint infections? a systematic review and meta-analysis

What is the best cutoff point of leukocyte esterase for diagnosis of periprosthetic joint infections? a systematic review and meta-analysis

Abstract Background Periprosthetic joint infection (PJI) is a significant complication following total joint arthroplasty that demands rapid, accurate diagnosis. The leukocyte esterase (LE) test shows promise, but studies vary in cut-off values and omit the centrifugation’s effect. In this study, we...

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Bibliographic Details
Main Authors: Mohammad Poursalehian, Ali Soltani Farsani, Pouya Tabatabaei Irani, Mohammad Ayati Firoozabadi, Javad Parvizi, SM Javad Mortazavi
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Arthroplasty
Subjects:
Periprosthetic joint infection
Total joint arthroplasty
Leucocyte esterase test
Diagnostic accuracy
Centrifugation
Biomarkers
Online Access:https://doi.org/10.1186/s42836-025-00325-y
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https://doi.org/10.1186/s42836-025-00325-y

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