Adherence to life’s essential 8 is associated with delayed white matter agingResearch in context

Adherence to life’s essential 8 is associated with delayed white matter agingResearch in context

Summary: Background: The American Heart Association introduced Life’s Essential 8 (LE8) to promote cardiovascular health and longevity. However, its impact on brain ageing and interactions with genetic risk factors of dementia, such as APOE4, remains unclear. This study investigates the relationshi...

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Main Authors: Li Feng, Zhenyao Ye, Yezhi Pan, Rozalina G. McCoy, Braxton D. Mitchell, Peter Kochunov, Paul M. Thompson, Jie Chen, Menglu Liang, Thu T. Nguyen, Edmond Shenassa, Yan Li, Travis Canida, Hongjie Ke, Hwiyoung Lee, Song Liu, L. Elliot Hong, Chixiang Chen, David K.Y. Lei, Shuo Chen, Tianzhou Ma
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:EBioMedicine
Subjects:
Life’s essential 8
White matter
Brain age gap
Machine learning
APOE4
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396425001677
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