Using MUC2 mucin producing tumorigenic human goblet-like cells to uncover functional properties of the mucus barrier

Goblet cells are the guardians that produce MUC2 mucin that forms the protective mucus barrier as the first line of innate host defense against pathogen invasion while sustaining a healthy gut microbiota. Using an unbiased screen, we cloned a high LS174T colonic adenocarcinoma MUC2 mucin-producing g...

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Bibliographic Details
Main Authors: Hayley Gorman, France Moreau, Elise Beaupré, Nitin Nitin, Wesley F. Zandberg, Kirk Bergstrom, Paul M. K. Gordon, Antoine Dufour, Kris Chadee
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
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Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2542385
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