The Mechanisms of Catalysis by Metallo 𝛽-Lactamases
Class B 𝛽-lactamases or metallo-𝛽-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of 𝛽-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. There are no clinically useful inhibitors against MBLs which are responsible for the resistance of some bacteri...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2008-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2008/576297 |
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