Protection efficacy of mRNA-based SARS-CoV-2 variant vaccine in non-human primates

Protection efficacy of mRNA-based SARS-CoV-2 variant vaccine in non-human primates

The rapid emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that evade immunity elicited by vaccination has posed a global challenge to the control of the coronavirus disease 2019 (COVID-19) pandemic. Therefore, developing countermeasures that broadly protect against...

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Bibliographic Details
Main Authors: Dongrong Yi, Yongxin Zhang, Jing Wang, Qian Liu, Ling Ma, Quanjie Li, Saisai Guo, Ruifang Zheng, Xiaoyu Li, Xingong Li, Yijie Dong, Shuaiyao Lu, Weiguo Zhang, Xiaozhong Peng, Shan Cen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
SARS-CoV-2
mRNA-LNP
Vaccine
Spike glycoprotein
Non-human primate
Humoral immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352400460X
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