Discovery of triazole derivatives for biofilm disruption, anti-inflammation and metal ion chelation

In the face of bacterial hazards to human health and resistance to multiple antibiotics, there is an urgent need to develop new antibiotics to meet the challenge. In this paper, the triazolyl heterocyclic (3-amino-1,2,4-triazole, D) was synthesised efficiently using thiourea as starting material. Fi...

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Bibliographic Details
Main Authors: Shuang Hong, Hongzhi Lu, Dawei Tian, Yue Chang, Qi Lu, Feng Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1545259/full
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