Comparative evaluation of in-house ELISA and two commercial serological assays for the detection of antibodies against SARS-CoV-2

Comparative evaluation of in-house ELISA and two commercial serological assays for the detection of antibodies against SARS-CoV-2

Abstract The in-house ELISA SARS-CoV-2 serological assay, developed by the Armauer Hansen Research Institute (AHRI) in Ethiopia, measures anti-SARS-CoV-2 receptor binding domain (RBD) antibodies. This study aimed to compare the performance of our cost-effective in-house ELISA with two established co...

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Main Authors: Dabesa Gobena, Esayas Kebede Gudina, Tizta Tilahun Degfie, Tsinuel Girma, Getu Gebre, Alemseged Abdissa, Fikadu G. Tafesse, Tesfaye Gelanew, Zeleke Mekonnen
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
In-house ELISA
Corcordance
Serological assay
Pre-Omicron
Ethiopia
Online Access:https://doi.org/10.1038/s41598-025-97050-y
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https://doi.org/10.1038/s41598-025-97050-y

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