Mitochondrial-derived peptides, HNG and SHLP3, protect cochlear hair cells against gentamicin

Abstract Preservation of hair cells is critical for maintaining hearing function, as damage to sensory cells potentially leads to irreparable sensorineural hearing loss. Hair cell loss is often associated with inflammation and oxidative stress. One promising class of bioactive peptides is mitochondr...

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Bibliographic Details
Main Authors: Yu Lu, Ewelina M. Bartoszek, Maurizio Cortada, Daniel Bodmer, Soledad Levano Huaman
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-02215-9
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