Clinical significance of measuring ADAMTS-13, its inhibitor and von Willebrand factor in obstetric and gynecological practice

Clinical significance of measuring ADAMTS-13, its inhibitor and von Willebrand factor in obstetric and gynecological practice

ADAMTS-13 is a crucial metalloproteinase involved in liberating fragments of von Willebrand factor (vWF) into the plasma as well as regulating its activity by cleaving "ultra-large" multimers into smaller and less active counterparts. Many pathological conditions, including those emerged d...

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Main Authors: K. N. Grigoreva, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, D. A. Ponomarev, K. Yu. Tsvetnova, D. A. Doronicheva, A. R. Mamaeva, K. V. Mekhedova, G. Rizzo, J.-C. Gris, I. Elalamy, A. D. Makatsariya
Format: Article
Language:Russian
Published: IRBIS LLC 2021-03-01
Series:Акушерство, гинекология и репродукция
Subjects:
von willebrand factor
adamts-13
thrombotic thrombocytopenic purpura
Online Access:https://www.gynecology.su/jour/article/view/936
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