Naturally Occurring Polymorphisms of the Mouse Gammaretrovirus Receptors CAT-1 and XPR1 Alter Virus Tropism and Pathogenicity

Gammaretroviruses of several different host range subgroups have been isolated from laboratory mice. The ecotropic viruses infect mouse cells and rely on the host CAT-1 receptor. The xenotropic/polytropic viruses, and the related human-derived XMRV, can infect cells of other mammalian species and us...

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Bibliographic Details
Main Author: Christine A. Kozak
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2011/975801
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