Intracellular Pseudomonas aeruginosa persist and evade antibiotic treatment in a wound infection model.

Persistent bacterial infections evade host immunity and resist antibiotic treatments through various mechanisms that are difficult to evaluate in a living host. Pseudomonas aeruginosa is a main cause of chronic infections in patients with cystic fibrosis (CF) and wounds. Here, by immersing wounded z...

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Main Authors: Stéphane Pont, Flore Nilly, Laurence Berry, Anne Bonhoure, Morgan A Alford, Mélissande Louis, Pauline Nogaret, Manjeet Bains, Olivier Lesouhaitier, Robert E W Hancock, Patrick Plésiat, Anne-Béatrice Blanc-Potard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012922
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