A fast approach for structural and evolutionary analysis based on energetic profile protein comparison

Abstract In structural bioinformatics, the efficiency of predicting protein similarity, function, and evolutionary relationships is crucial. Our approach proposed herein leverages protein energy profiles derived from a knowledge-based potential, deviating from traditional methods relying on structur...

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Bibliographic Details
Main Authors: Peyman Choopanian, Jaan-Olle Andressoo, Mehdi Mirzaie
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57374-9
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