HIMA2: high-dimensional mediation analysis and its application in epigenome-wide DNA methylation data
Abstract Mediation analysis plays a major role in identifying significant mediators in the pathway between environmental exposures and health outcomes. With advanced data collection technology for large-scale studies, there has been growing research interest in developing methodology for high-dimens...
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| Main Authors: | Chamila Perera, Haixiang Zhang, Yinan Zheng, Lifang Hou, Annie Qu, Cheng Zheng, Ke Xie, Lei Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-07-01
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| Series: | BMC Bioinformatics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12859-022-04748-1 |
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