HIMA2: high-dimensional mediation analysis and its application in epigenome-wide DNA methylation data

Abstract Mediation analysis plays a major role in identifying significant mediators in the pathway between environmental exposures and health outcomes. With advanced data collection technology for large-scale studies, there has been growing research interest in developing methodology for high-dimens...

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Bibliographic Details
Main Authors: Chamila Perera, Haixiang Zhang, Yinan Zheng, Lifang Hou, Annie Qu, Cheng Zheng, Ke Xie, Lei Liu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-022-04748-1
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