The spatial orientation of histidine via five-armed alkylamino siloxane improved the properties of the cationic gene delivery vector

The efficiency of gene transfection using cationic polymers primarily depends on factors such as compact polyplex formation, cellular uptake, endosomal escape, cytoplasmic transport, nuclear entry, and the dissociation and release of plasmid from the polyplex. These factors can be manipulated throug...

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Bibliographic Details
Main Authors: Viola B. Morris, Chandra P. Sharma
Format: Article
Language:English
Published: ELS Publishing (ELSP) 2024-11-01
Series:Biofunctional Materials
Subjects:
Online Access:https://elsp-homepage.oss-cn-hongkong.aliyuncs.compaper/journal/open/BM/2024/BM-240100025.pdf
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