Evaluation of the Antinociceptive Effect of Sesamin: Role of 5HT<sub>1A</sub> Serotonergic Receptors

Evaluation of the Antinociceptive Effect of Sesamin: Role of 5HT<sub>1A</sub> Serotonergic Receptors

<b>Background/Objectives:</b> Sesame (<i>Sesamum indicum</i> L.) is used in folk medicine to treat painful disorders. Sesamin is the main lignan found in this plant; however, its antinociceptive potential has scarcely been studied. The aim was to investigate the antinocicepti...

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Main Authors: Roberto Camacho-Cruz, David Francisco Alcalá-Hernández, Juan Carlos Huerta-Cruz, Jesús Arrieta-Valencia, María Elena Sánchez-Mendoza, Francisco Javier Flores-Murrieta, Andrés Navarrete, Juan Gerardo Reyes-García, Héctor Isaac Rocha-González
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceutics
Subjects:
diclofenac
gabapentin
inflammatory pain
neuropathic pain
serotonergic receptors
sesamin
Online Access:https://www.mdpi.com/1999-4923/17/3/330
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