Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa.

Analysis of host responses to Mycobacterium tuberculosis antigens in a multi-site study of subjects with different TB and HIV infection states in sub-Saharan Africa.

<h4>Background</h4>Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are relevant to protective immunity...

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Main Authors: Jayne S Sutherland, Maeve K Lalor, Gillian F Black, Lyn R Ambrose, Andre G Loxton, Novel N Chegou, Desta Kassa, Adane Mihret, Rawleigh Howe, Harriet Mayanja-Kizza, Marie P Gomez, Simon Donkor, Kees Franken, Willem Hanekom, Michel R Klein, Shreemanta K Parida, W Henry Boom, Bonnie A Thiel, Amelia C Crampin, Martin Ota, Gerhard Walzl, Tom H M Ottenhoff, Hazel M Dockrell, Stefan H E Kaufmann, GCGH Biomarkers for TB consortium
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0074080
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https://doi.org/10.1371/journal.pone.0074080

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