Single-cell and spatial transcriptomics reveals an anti-tumor neutrophil subgroup in microwave thermochemotherapy-treated lip cancer

Abstract Microwave thermochemotherapy (MTC) has been applied to treat lip squamous cell carcinoma (LSCC), but a deeper understanding of its therapeutic mechanisms and molecular biology is needed. To address this, we used single-cell transcriptomics (scRNA-seq) and spatial transcriptomics (ST) to hig...

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Bibliographic Details
Main Authors: Bingjun Chen, Huayang Fan, Xin Pang, Zeliang Shen, Rui Gao, Haofan Wang, Zhenwei Yu, Tianjiao Li, Mao Li, Yaling Tang, Xinhua Liang
Format: Article
Language:English
Published: Nature Publishing Group 2025-05-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-025-00366-8
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