A Spatially Distributed Microneedle System for Bioorthogonal T Cell‐Guided Cancer Therapy

A Spatially Distributed Microneedle System for Bioorthogonal T Cell‐Guided Cancer Therapy

Abstract Chimeric antigen receptor (CAR)‐T cell therapy represents a promising strategy for cancer treatment. However, the diversity of solid tumor antigens and the poor infiltration of CAR‐T cells significantly hinder the efficacy of CAR‐T therapies against tumors. Here, a spatially distributed mic...

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Bibliographic Details
Main Authors: Lanya Li, Fei Wang, Shushan Mo, Junyao Deng, Xueyi Wang, Jiacong Ai, Yingxian Xiao, Yan Zeng, Qishan Li, Yixin Zhang, Limin Cai, Zhenhua Li
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
bioorthogonal reaction
lymph node
solid tumors
spatially distributed microneedle
T cell migration
Online Access:https://doi.org/10.1002/advs.202416841
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https://doi.org/10.1002/advs.202416841

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