Targeting SLC7A5 in lung squamous cell carcinoma: implications for cancer metabolism shift and boron neutron capture therapy resistance

Targeting SLC7A5 in lung squamous cell carcinoma: implications for cancer metabolism shift and boron neutron capture therapy resistance

Abstract Squamous cell carcinoma (SCC) poses a significant global health challenge due to the lack of effective treatments. Boron neutron capture therapy (BNCT), a targeted particle therapy, has shown promising results in various cancers. SLC7A5, a transporter of essential amino acids and boronophen...

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Main Authors: Yen-Ju Lin, Yu-Cheng Wu, Yu-Jui Liu, Wei-Chen Yeh, Yi-Chen Huang, Shen-Ao Zhang, Alvin Chen, Ming-Yi Zheng, Hong-Ming Liu, Fong-In Chou, Shien-Tung Pan, Min-Yuan Chou, Yu-Ting Chou
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-025-00568-z
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https://doi.org/10.1038/s41389-025-00568-z

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