Reprogramming Lung Redox Homeostasis by NIR Driven Ultra‐Small Pd Loaded Covalent Organic Framework Inhibits NF‐κB Pathway for Acute Lung Injury Immunotherapy

Reprogramming Lung Redox Homeostasis by NIR Driven Ultra‐Small Pd Loaded Covalent Organic Framework Inhibits NF‐κB Pathway for Acute Lung Injury Immunotherapy

Abstract Acute lung injury (ALI) refers to damage to lung related cells, typically caused by an uncontrollable inflammatory response, and over‐generated reactive oxygen species (ROS). Increasing evidence suggests that reprogramming lung redox homeostasis holds significant potentials for the clinical...

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Main Authors: Doudou Lei, Lin Liao, Tao Qin, Xiaoxuan Guan, Kunpeng Duan, Zhiwei Gao, Weiqian Jin, Mingjing Yin, Ke Zhang, Yan Liu, Yin Chen, Huyang Gao, Jiaxiao Li, Feifei Huang, Wenjing Liu, Chengde Xia, Bailei Wang, Hualin Huang, Shengqiu Lv, Qiang Zhi, Jiahao Huang, Ming Gao, Junyu Lu
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
acute lung injury
covalent organic framework
M2 directional polarization
NF‐κB signaling pathway
ROS scavenging
Online Access:https://doi.org/10.1002/advs.202413697
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https://doi.org/10.1002/advs.202413697

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