Enhancing adipogenesis in Wharton’s jelly multipotent mesenchymal stromal cells through lipidomic insights and fatty acid supplementation

Enhancing adipogenesis in Wharton’s jelly multipotent mesenchymal stromal cells through lipidomic insights and fatty acid supplementation

Abstract Wharton’s Jelly multipotent mesenchymal stromal cells (WJ-MSCs) hold potential for regenerative medicine, particularly in soft tissue engineering. However, their adipogenic differentiation capacity is inferior to adipose tissue-derived MSCs (AT-MSCs). This study aimed to optimize adipogenic...

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Bibliographic Details
Main Authors: Olena Rogulska, Eliska Vavrinova, Irena Vackova, Katarina Smolkova, Yuriy Petrenko
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Multipotent mesenchymal stromal cells
Adipogenic differentiation
Lipidomic profile
Wharton’s jelly
Adipose tissue
Triglycerides
Online Access:https://doi.org/10.1038/s41598-025-16867-9
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https://doi.org/10.1038/s41598-025-16867-9

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