Loss of Cell-Cell Contact Inhibits Cellular Differentiation of α-Catenin Knock Out P19 Embryonal Carcinoma Cells and Their Colonization into the Developing Mouse Embryos

Loss of Cell-Cell Contact Inhibits Cellular Differentiation of α-Catenin Knock Out P19 Embryonal Carcinoma Cells and Their Colonization into the Developing Mouse Embryos

Cadherin−catenin cell−cell adhesion complexes, composed of cadherin, β-catenin or plakoglobin, and α-catenin (α-cat) molecules, are crucial for maintaining cell−cell contact and are commonly referred to as “adherens junctions (AJs).” Inactivating this system leads to loss of cell−cell contact and de...

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Main Authors: Masahiro Sato, Emi Inada, Naoko Kubota, Masayuki Ozawa
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:BioTech
Subjects:
cell–cell contact
cadherin−catenin complex
embryoid body
cellular differentiation
P19 cells
embryonal carcinoma cell
Online Access:https://www.mdpi.com/2673-6284/13/4/41
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