The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease

The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease

Abstract Background Ginsenoside Rd (G-Rd), found in Panax species, has shown therapeutic potential against metabolism-associated fatty liver disease (MAFLD), but its mechanism has not been well elucidated. This study investigated the key mechanisms of G-Rd in modulating the gut microbiome and lipid...

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Main Authors: Wenjing Liu, Xian Zhou, Liyu Xiao, Xiaolan Huang, Dennis Chang, Xiaomei Zhong, Minjie Zeng, Yanfang Xian, Yanfang Zheng, Wei Huang, Rui Huang, Mingqing Huang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Chinese Medicine
Subjects:
Ginsenoside Rd
MAFLD
Gut microbiota
Lipid peroxidation
Ferroptosis
Nrf2
Online Access:https://doi.org/10.1186/s13020-025-01121-1
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https://doi.org/10.1186/s13020-025-01121-1

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