Investigating the effects of global gene knockout of MrgF on motor performance and pain sensitivity in mice

Abstract Mas-related G protein-coupled receptors (Mrgs) are a subset of GPCRs linked to pain modulation. MrgF was identified as an orphan Mrg whose function and ligand remain unclear. In this study, in addition to its expression in the dorsal root ganglia (DRG), the primary afferent center that tran...

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Bibliographic Details
Main Authors: Xuejiao Chen, Yan Chen, Runzhe Shu, Shunyuan Lu, Ming-Min Gu, Chunling Shen, Zhugang Wang, Xiaofang Cui
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Hereditas
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Online Access:https://doi.org/10.1186/s41065-025-00377-9
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