Multifaceted Approaches in Epithelial Cell Adhesion Molecule-Mediated Circulating Tumor Cell Isolation

Multifaceted Approaches in Epithelial Cell Adhesion Molecule-Mediated Circulating Tumor Cell Isolation

Circulating tumor cells (CTCs) are pivotal in cancer metastasis and serve as valuable biomarkers for diagnosis, prognosis, and treatment monitoring. Traditional CTC capture methods predominantly utilize the epithelial cell adhesion molecule (EpCAM) as a marker for isolation. However, the heterogenei...

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Bibliographic Details
Main Authors: Dora Szerenyi, Gabor Jarvas, Andras Guttman
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
Subjects:
liquid biopsy
CTC
surface markers
EMT
immuno-affinity
label-free isolation
Online Access:https://www.mdpi.com/1420-3049/30/5/976
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