Single and Multiple Doses of Seladelpar Decrease Diurnal Markers of Bile Acid Synthesis in Mice

Peroxisome proliferator–activated receptors (PPARs) modulate bile metabolism and are important therapeutic options in cholestatic diseases. This study was aimed at understanding the effects of single and multiple doses of seladelpar, a PPARδ (peroxisome proliferator–activated receptor delta) agonist...

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Bibliographic Details
Main Authors: Edward E. Cable, Jeffrey W. Stebbins, Jeff D. Johnson, Yun-Jung Choi, Jiangao Song, Sole Gatto, Matthew Onorato, Charles A. McWherter
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/ppar/5423221
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