The Immunologic Downsides Associated with the Powerful Translation of Current COVID-19 Vaccine mRNA Can Be Overcome by Mucosal Vaccines

The action of mRNA-based vaccines requires the expression of the antigen in cells targeted by lipid nanoparticle–mRNA complexes. When the vaccine antigen is not fully retained by the producer cells, its local and systemic diffusion can have consequences depending on both the levels of antigen expres...

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Bibliographic Details
Main Author: Maurizio Federico
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/12/11/1281
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