Network toxicology combined with molecular docking technology to explore the molecular mechanism of amatoxin causing liver injury

Abstract As one of the most toxic molecules in the fungal kingdom, amatoxin exhibit exceptional thermal stability and acid resistance. Once ingested, these compounds are rapidly absorbed and transported unimpeded to vital organs. They disrupt cellular metabolism by inhibiting nucleic acid and protei...

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Bibliographic Details
Main Authors: Chenglin Wang, Xin Wang, Yaxing Deng, Yingchun Hu, Li Hu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-11720-5
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