ATG16L1 restrains macrophage NLRP3 activation and alveolar epithelial cell injury during septic lung injury
Abstract Background The lung is the organ most commonly affected by sepsis. Additionally, acute lung injury (ALI) resulting from sepsis is a major cause of death in intensive care units. Macrophages are essential for maintaining normal lung physiological functions and are implicated in various pulmo...
Saved in:
| Main Authors: | Yan Bai, Xinyu Zhan, Qing Zhu, Xingyue Ji, Yingying Lu, Yiyun Gao, Fei Li, Zhu Guan, Haoming Zhou, Zhuqing Rao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-04-01
|
| Series: | Clinical and Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ctm2.70289 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Research and progress of cGAS/STING/NLRP3 signaling pathway: a mini review
by: Ke-qian Chen, et al.
Published: (2025-05-01) -
Epithelial Atg5 Deficiency Intensifies Caspase‐11 Activation, Fueling Extracellular mtDNA Release to Activate cGAS–STING–NLRP3 Axis in Macrophages During Pseudomonas Infection
by: Junyi Wang, et al.
Published: (2025-07-01) -
Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway
by: Xin Zhou, et al.
Published: (2025-05-01) -
CMPK2 promotes NLRP3 inflammasome activation via mtDNA‐STING pathway in house dust mite‐induced allergic rhinitis
by: YaoMing Zheng, et al.
Published: (2025-01-01) -
NLRP3 inflammasome: a key player in neonatal brain injury
by: Cagla Kiser, et al.
Published: (2025-07-01)