ATG16L1 restrains macrophage NLRP3 activation and alveolar epithelial cell injury during septic lung injury

Abstract Background The lung is the organ most commonly affected by sepsis. Additionally, acute lung injury (ALI) resulting from sepsis is a major cause of death in intensive care units. Macrophages are essential for maintaining normal lung physiological functions and are implicated in various pulmo...

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Bibliographic Details
Main Authors: Yan Bai, Xinyu Zhan, Qing Zhu, Xingyue Ji, Yingying Lu, Yiyun Gao, Fei Li, Zhu Guan, Haoming Zhou, Zhuqing Rao
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Clinical and Translational Medicine
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Online Access:https://doi.org/10.1002/ctm2.70289
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