STAT3 promotes IFNγ/TNFα‐induced muscle wasting in an NF‐κB‐dependent and IL‐6‐independent manner

Abstract Cachexia is a debilitating syndrome characterized by involuntary muscle wasting that is triggered at the late stage of many cancers. While the multifactorial nature of this syndrome and the implication of cytokines such as IL‐6, IFNγ, and TNFα is well established, we still do not know how v...

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Bibliographic Details
Main Authors: Jennifer F Ma, Brenda J Sanchez, Derek T Hall, Anne‐Marie K Tremblay, Sergio Di Marco, Imed‐Eddine Gallouzi
Format: Article
Language:English
Published: Springer Nature 2017-03-01
Series:EMBO Molecular Medicine
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Online Access:https://doi.org/10.15252/emmm.201607052
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