An independently tunable dual control system for RNAi complementation in Trypanosoma brucei.

An independently tunable dual control system for RNAi complementation in Trypanosoma brucei.

Trypanosoma brucei is a tractable protist parasite for which many genetic tools have been developed to study novel biology. A striking feature of T. brucei is the catenated mitochondrial DNA network called the kinetoplast DNA (kDNA) that is essential for parasite survival and life cycle completion....

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Main Authors: Raveen Armstrong, Matt J Romprey, Henry M Raughley, Stephanie B Delzell, Matthew P Frost, James Chambers, Grace G Garman, David Anaguano, Michele M Klingbeil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0321334
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https://doi.org/10.1371/journal.pone.0321334

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