Anti-biofilm peptides can rescue fluconazole and amphotericin B efficacies against Candida albicans

Anti-biofilm peptides can rescue fluconazole and amphotericin B efficacies against Candida albicans

Abstract Candida albicans infections are a global health thread and challenge healthcare environments due to acquired resistances against prominent antifungals like amphotericin B and fluconazole, which additionally have severe adverse effects. The peptide Pom-1 originally isolated from the freshwat...

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Main Authors: Ann-Kathrin Kissmann, Vanessa Mildenberger, Markus Krämer, Daniel Alpízar-Pedraza, Ernesto M. Martell-Huguet, Julio A. Perez-Erviti, Ahmet Cetinkaya, Joanna Pietrasik, Anselmo J. Otero-Gonzalez, Carolina Firacative, Armando Rodríguez, Ludger Ständker, Tanja Weil, Steffen Stenger, Frank Rosenau
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Antimicrobial peptides
Amphotericin B
Candida albicans
Fluconazole
Resistance
Online Access:https://doi.org/10.1038/s41598-025-10315-4
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https://doi.org/10.1038/s41598-025-10315-4

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