Telocyte-derived exosomes promote angiogenesis and alleviate acute respiratory distress syndrome via JAK/STAT-miR-221-E2F2 axis

Telocyte-derived exosomes promote angiogenesis and alleviate acute respiratory distress syndrome via JAK/STAT-miR-221-E2F2 axis

Abstract Acute respiratory distress syndrome (ARDS) is characterized by severe respiratory failure and significant inflammation, leading to vascular and epithelial cell damage. The absence of effective pharmacologic treatments underscores the need for novel therapeutic approaches. Telocytes (TCs), a...

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Bibliographic Details
Main Authors: Rongrong Gao, Xu Zhang, Huihui Ju, Yile Zhou, Luoyue Yin, Liuke Yang, Pinwen Wu, Xia Sun, Hao Fang
Format: Article
Language:English
Published: Springer 2025-04-01
Series:Molecular Biomedicine
Subjects:
Acute respiratory distress syndrome
Telocyte
Exosomal microRNA
MiR-221
Online Access:https://doi.org/10.1186/s43556-025-00259-6
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https://doi.org/10.1186/s43556-025-00259-6

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