Hepatitis C Virus Evasion from RIG-I-Dependent Hepatic Innate Immunity

Exposure to hepatitis C virus (HCV) usually results in persistent infection that often develops into chronic liver disease. Interferon-alpha (IFN) treatment comprises the foundation of current approved therapy for chronic HCV infection but is limited in overall efficacy. IFN is a major effector of i...

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Bibliographic Details
Main Authors: Helene Minyi Liu, Michael Gale
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2010/548390
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