Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes

Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes

Abstract We used a novel approach of cytostatically induced leucocyte depletion and subsequent reconstitution with leucocytes deprived of classical (inflammatory/Gr1hi) or non‐classical (resident/Gr1lo) monocytes to dissect their differential role in atheroprogression under high‐fat diet (HFD). Apol...

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Main Authors: Oliver Soehnlein, Maik Drechsler, Yvonne Döring, Dirk Lievens, Helene Hartwig, Klaus Kemmerich, Almudena Ortega‐Gómez, Manuela Mandl, Santosh Vijayan, Delia Projahn, Christoph D. Garlichs, Rory R. Koenen, Mihail Hristov, Esther Lutgens, Alma Zernecke, Christian Weber
Format: Article
Language:English
Published: Springer Nature 2013-02-01
Series:EMBO Molecular Medicine
Subjects:
atherosclerosis
chemokine
mobilization
monocyte
recruitment
Online Access:https://doi.org/10.1002/emmm.201201717
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https://doi.org/10.1002/emmm.201201717

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