Species specificity and specificity diversity (SSD) framework: a novel method for detecting the unique and enriched species associated with disease by leveraging the microbiome heterogeneity

Abstract Background Differentiating the microbiome changes associated with diseases is challenging but critically important. Majority of existing efforts have been focused on a community level, but the discerning power of community or holistic metrics such as diversity analysis seems limited. This p...

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Bibliographic Details
Main Author: Zhanshan Sam Ma
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-024-02024-7
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