Surgical techniques and outcome assessment of a novel vascularized orthotopic rodent whole eye transplantation model.

Currently there are no surgical solutions to restore vision in the irreversibly blind. Whole eye transplantation (WET), is an appealing surgical approach for restoration, replacement, and reconstruction of nonfunctioning eyes. Development of a reliable animal model to test the integrity and function...

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Main Authors: Yang Li, Chiaki Komatsu, Lin He, Maxine R Miller, Jila Noori, Yolandi van der Merwe, Leon C Ho, Ian A Rosner, Joshua M Barnett, Kayvon Jabbari, Gadi Wollstein, Richard A Bilonick, Valeria L N Fu, Mario G Solari, An-Jey A Su, Kevin C Chan, Joel S Schuman, Kia M Washington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0311392
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