Nrf2 induction potency of plant-derived compounds determined using an antioxidant response element luciferase reporter and conventional NAD(P)H-quinone acceptor oxidoreductase 1 activity assay

Abstract Objective Various plants have been reported to contain compounds that promote the transcriptional activity of Nuclear factor erythroid 2-related factor 2 (Nrf2) to induce a set of xenobiotic detoxifying enzymes, such as NAD(P)H-quinone acceptor oxidoreductase 1 (NQO1), via the antioxidant r...

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Bibliographic Details
Main Authors: Erina Tamaru, Daichi Kokubu, Yusuke Ushida, Ken Itoh
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Research Notes
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Online Access:https://doi.org/10.1186/s13104-024-07038-6
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